Learn more about if enclomiphene can increase testosterone levels in men, and what studies have been done on the subject.
If you are a man dealing with low Testosterone (hypogonadism), you used to have only a couple of options. Either learn to live with the lower levels, or look into getting a prescription for a medication that contains Testosterone, generally in injectable, cream, or gel form.
Testosterone replacement treatments like these do a pretty good job at increasing those Testosterone levels, because, well, it is raw Testosterone you are using.
But, using raw Testosterone replacement has been shown to decrease sperm production and fertility, making Testosterone replacement for men who still want to have kids in the near future a tricky situation.
One potential emerging alternative off-label treatment that some doctors are turning to is called enclomiphene. Enclomiphene citrate is one isomer of the commercially available medication Clomid (clomiphene). Enclomiphene has been found to help increase Testosterone levels in men that have low Testosterone, potentially without the decrease in fertility like you can see with raw Testosterone replacement.
Below, we will dive deeper into the potential Testosterone improvements of using enclomiphene, including how much you can expect levels to increase by (according to the studies).
While there is not a huge amount of studies that have looked into enclomiphene alone (not as a part of clomiphene), we do have a few smaller studies that back up its ability to increase Testosterone levels.
One 2013 study had 44 men with low Testosterone randomized into groups to take either 6.25mg of enclomiphene, 12.5mg of enclomiphene, 25mg of enclomiphene, or the usual topical Testosterone (Androgel) daily for 6 weeks. At the end of the study, the results showed that total Testosterone (TT) numbers increased across all treatment groups, whether the men used enclomiphene or topical Testosterone.
Another study published in 2015 had 265 hypogonadal men use either 12.5mg of enclomiphene, 25mg of enclomiphene, or a Testosterone gel daily for 16 weeks, and then measured their total Testosterone as well as sperm count changes. Both enclomiphene doses and the Testosterone gel showed increases in Testosterone levels up to the normal range. But, the Testosterone gel group showed reduced sperm counts while the enclomiphene groups had maintained sperm counts.
More studies need to be done with larger numbers of participants to figure out exactly what to expect with enclomiphene use. But, the information we have so far on just how much enclomiphene can possibly increase total Testosterone levels will need to be gleaned from the studies listed above.
In the 2013 study, men were enrolled with low Testosterone levels reported as less than 350ng/DL, and by the end of the study their total Testosterone levels increased to a mean concentration of 604ng/DL.
For the 2015 study mentioned above, the participants were enrolled with total Testosterone levels less than 300ng/DL, and by the end of the first 4 weeks, the total Testosterone levels were reported to reach a steady state above 400ng/DL (closer to a mean of 450ng/DL). These increased levels remained for the remainder of the 16 weeks until the men stopped using enclomiphene.
Here at Strut Health, we offer a compounded prescription enclomiphene medication that we like to call Strut Mojo. This medication can also be prescribed to contain a dose of daily tadalafil (generic Cialis) to help men who are also dealing with symptoms of erectile dysfunction.
To get started on this medication, we need to test your baseline Testosterone levels to make sure Testosterone increases are appropriate for you. But, don’t worry, we make this step easy by offering a Testosterone test kit directly from us. Once we receive your results, our doctors can determine the appropriateness of this medication for you, and come up with an enclomiphene treatment plan, if you are a good candidate for use. Then, your medication will be shipped to your front door with our free shipping.
To get started, simply start your free online telemedicine consultation for Strut Mojo (enclomiphene with or without tadalafil) today.